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Rosiglitazone is an anti-diabetic drug from the thiazolidinedione class. Like other thiazolidinediones, its mechanism of action is by activation of the intracellular receptor class of the peroxisome proliferator-activated receptors (PPARs), specifically PPAR-gamma.
Avandia (rosiglitazone) is an oral diabetes medicine that helps control blood sugar levels. Avandia is for people with type 2 diabetes. Rosiglitazone is sometimes used in combination with other medicines, but it is not for treating type 1 diabetes.
The efficacy of thiazolidinediones, as compared with other oral glucose-lowering medications, in maintaining long-term glycemic control in type 2 diabetes is not known. We evaluated rosiglitazone, metformin, and glyburide as initial treatment for recently diagnosed type 2 diabetes in a double-blind
Matrix Pathobiology Rosiglitazone Abrogates Bleomycin-Induced Scleroderma and Blocks Profibrotic Responses Through Peroxisome Proliferator-Activated
Packaging 10, 50 mg in glass bottle Biochem/physiol Actions Rosiglitazone is a potent agonist for PPARγ with an EC50 of 43 nM for the human receptor.
Rosiglitazone is widely used to treat patients with type 2 diabetes mellitus, but its effect on cardiovascular morbidity and mortality has not been determined. Data were combined by means of a fixed-effects model. In the 42 trials, the mean age of the subjects was approximately 56 years, and the
Background. Rosiglitazone is an insulin sensitiser used in combination with metformin, a sulfonylurea, or both, for lowering blood glucose in people with type 2 diabetes.
Treatment of type 1 and type 2 diabetes include insulin, a diabetic diet, exercise, and medication. Guidelines for diabetes treatment varies by person. Learn about specific medications including side effects, and diet plan programs for diabetes, and other diabetes treatment options.
The endocrine system consists of a number of glands -- including the pineal gland, pituitary gland, thyroid gland, and adrenal gland -- that produce and secrete hormones that circulate within the body.
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